Cefuroxime — Uses, Dosage, Side Effects, and Practical Tips

Cefuroxime is a common antibiotic doctors use for chest infections, sinusitis, ear infections, skin infections, and some urinary tract infections. It’s a second‑generation cephalosporin that kills bacteria. It’s available as oral tablets (cefuroxime axetil) and as IV/IM forms in hospitals.

Thinking you need it right away? Don’t self‑prescribe. Antibiotics only work for bacterial infections, not colds or most sore throats. See a clinician who can confirm the cause and the right dose for your case.

How to take cefuroxime

Oral cefuroxime axetil is usually taken twice a day. Typical adult doses are 250–500 mg every 12 hours for common infections. For more serious infections, doctors might use 500 mg twice daily or switch to IV cefuroxime in the hospital. For early Lyme disease some guidelines use 500 mg twice daily for 14–21 days. Always follow your prescriber's exact instructions.

Take the tablet with food — that helps your body absorb it better. Finish the full course even if you feel better after a few days. Stopping early can let bacteria survive and come back resistant.

Warnings and side effects

Most people tolerate cefuroxime fine, but expect possible mild stomach upset, nausea, diarrhea, or yeast infections. A serious concern is allergic reaction: if you get hives, swelling, or trouble breathing, stop the drug and get emergency care. If you have a known severe penicillin allergy, tell your doctor—cross‑reactivity is uncommon but possible.

Antibiotics can trigger Clostridioides difficile (C. diff) — watch for frequent, watery diarrhea or fever starting during or after treatment. If that happens, contact your provider right away.

Adjustments may be needed for reduced kidney function. Some drugs interact with cefuroxime — probenecid raises cefuroxime levels, and it may slightly affect blood thinners like warfarin. Tell your prescriber about all medicines you take, including supplements.

Storage is simple: keep tablets at room temperature away from moisture. Don’t share antibiotics, and don’t use an old prescription for a new illness. If you’re pregnant or breastfeeding, mention it; cefuroxime is commonly used in pregnancy but your doctor will weigh risks and benefits.

Where to get it safely? Use licensed pharmacies or your clinic. Online options exist but pick verified sites that require prescriptions. If cost is a concern, ask your provider about generic cefuroxime — it’s effective and cheaper.

Missed dose? Take it as soon as you remember unless it’s nearly time for the next dose. Don't double up to catch up. If you vomit within an hour of taking the tablet, check with your doctor about repeating the dose. Keep an alarm set to stay on schedule—antibiotics work best with consistent levels in your blood.

For kids, dosing depends on weight; doctors prescribe a suspension. Always use the measuring cup. Watch for unusual rashes or behavior changes and call the clinic right away if you're unsure.

Questions for your prescriber: What dose and how long? Any tests needed? Should I avoid anything while taking it? Getting clear answers will keep treatment simple and effective.