Augmentin: What It Is and How to Use It Safely

Augmentin is a combination antibiotic that pairs amoxicillin with clavulanate. The clavulanate blocks bacterial enzymes that would normally destroy amoxicillin, so the drug can kill tougher bacteria. That makes Augmentin a go-to for infections where plain amoxicillin might fail.

How Augmentin is used

Doctors prescribe Augmentin for many common infections: sinusitis, ear infections (otitis media), bronchitis, some skin infections, and certain urinary tract infections. It comes as tablets, chewables, and a liquid suspension. Typical adult doses are either 875/125 mg twice daily or 500/125 mg three times daily, but your doctor will pick the best dose based on the infection and your health.

Kids get liquid versions with doses based on weight. If you have reduced kidney function, your provider will likely lower the dose or space it out more. Never guess your dose—check with your prescriber or pharmacist.

Side effects, warnings, and practical tips

The most common side effect is stomach upset and diarrhea. Taking Augmentin with food cuts down on nausea. If diarrhea is severe or contains blood, tell your doctor right away—this can be a sign of Clostridioides difficile infection, which needs treatment.

Allergic reactions to penicillin-type drugs happen. If you get hives, swelling of the face or throat, trouble breathing, or a sudden rash, go to the emergency room. Do not take Augmentin if you have a known penicillin allergy unless a specialist says it’s safe.

Rarely, Augmentin can affect the liver and cause jaundice. If you notice yellowing of the skin or eyes, dark urine, or persistent stomach pain, stop the medicine and contact your doctor. Also mention any other meds you take—some can interact or change how your body handles Augmentin.

For pregnancy and breastfeeding: Augmentin is commonly used and generally considered safe when needed, but only take it if your doctor recommends it. They’ll weigh the benefits and risks based on your situation.

Want fewer gut problems? Try taking Augmentin with a meal and consider a probiotic like Lactobacillus or Saccharomyces boulardii during and shortly after the course. Eat yogurt with live cultures if you like food-based options. Still, check with your clinician before adding supplements.

Finish the full course even if you feel better early. Stopping antibiotics too soon can let bacteria survive and come back stronger. If symptoms don’t improve in 48–72 hours, or if they get worse, call your healthcare provider—sometimes a different antibiotic or an additional test is needed.

Quick checklist: tell your doctor about allergies, kidney or liver issues, and other meds; take Augmentin with food; watch for severe diarrhea or allergic signs; finish the course. If you’re unsure about dosing or side effects, your pharmacist is a great quick resource.