Tag: amitriptyline

Tricyclic Antidepressants and Antihistamines: The Hidden Danger of Anticholinergic Overload

Tricyclic Antidepressants and Antihistamines: The Hidden Danger of Anticholinergic Overload

Combining tricyclic antidepressants like amitriptyline with first-gen antihistamines like Benadryl can cause dangerous anticholinergic overload-leading to confusion, memory loss, and increased dementia risk. Learn how to spot it and switch to safer options.

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