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Therapeutic Equivalence Codes (TE Codes) Explained: How Generic Drugs Are Approved and Substituted

Therapeutic Equivalence Codes (TE Codes) Explained: How Generic Drugs Are Approved and Substituted

  • 26.12.2025
  • Elliot Kelly
  • 12 Comments

Therapeutic Equivalence Codes (TE codes) are the FDA's system for determining which generic drugs can safely replace brand-name medications. Learn how they work, why they matter for your prescriptions, and when substitutions might not be ideal.

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