Fixed-dose combination drugs: what they are and why they exist
Fixed-dose combination drugs combine two or more medicines in one pill to improve adherence, reduce pill burden, and enhance treatment outcomes. They're widely used in heart disease, TB, and HIV, but not all combinations are justified.
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Renal Dosing for Metformin and SGLT2 Inhibitors: When to Adjust
Learn when and how to adjust metformin and SGLT2 inhibitor doses for kidney disease. Updated guidelines now allow safer use at lower eGFR levels-here’s what you need to know.
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How to Confirm Monitoring Labs and Follow-Up for Medications: A Practical Guide for Providers
Learn how labs verify and validate medication monitoring tests to ensure accurate dosing and prevent deadly errors. Essential reading for providers who rely on therapeutic drug monitoring results.
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Economic Impact of Patent Expiration: How Drug Prices Drop After Patents Expire
When pharmaceutical patents expire, drug prices typically drop by 80% or more as generics enter the market. This economic shift saves patients and insurers billions, but patent thickets and rebate systems often delay savings.
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Rifampin Induction: How It Lowers Anticoagulant and Antiviral Levels
Rifampin can drastically reduce levels of anticoagulants and antivirals by boosting liver enzymes, leading to dangerous treatment failures. Learn how this interaction works and what to do if you're on both.
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Lexapro vs. Other Antidepressants: Detailed Comparison
A clear side‑by‑side comparison of Lexapro (Escitalopram) with popular antidepressant alternatives, covering effectiveness, side effects, costs, and how to choose the right one.
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Medication‑Induced Lactic Acidosis: Risks, Signs & Management
Learn how medication‑induced lactic acidosis occurs, which drugs are risky, how to spot it early, and what steps save lives.
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Aromasin (Exemestane) vs Other Aromatase Inhibitors: Detailed Comparison
A clear, side‑by‑side comparison of Aromasin (Exemestane) and its main alternatives, covering mechanisms, benefits, risks, costs, and how to choose the right option.
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Pirfenidone and Idiopathic Pulmonary Fibrosis: How the Drug Slows Disease Progression
Explore how pirfenidone works, its clinical evidence, dosing, side effects, and how it helps slow idiopathic pulmonary fibrosis.
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Lurasidone and Social Functioning: How It Affects Relationships
Explore how lurasidone influences social functioning and relationships, with trial data, real-world insights, and practical tips for patients and caregivers.
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